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March 2017

Insights into ligand recognition and desensitization from the x-ray structure of a nicotinic receptor – Ryan Hibbs, UT Southwestern

March 30 @ 10:00 am - 11:00 am
MRC LMB: Max Perutz Lecture Theatre,

Nicotinic acetylcholine receptors are ligand gated ion channels that mediate fast chemical neurotransmission at the neuromuscular junction and play diverse signaling roles in the central nervous system. The vast majority of these and other pentameric receptors in the superfamily assemble as obligate heteromers. Here I will present methods we developed for expression and biochemical characterization of heteromeric ion channels and present the first X-ray crystal structure of a nicotinic receptor. The alpha4beta2 nicotinic receptor that we characterized structurally is the…

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Title to be confirmed – Dr János Réthelyi, School of Mental Health Sciences, Semmelweis University, Budapest

March 30 @ 12:30 pm
Seminar Room, Herchel Smith Building, Forvie Site.,

Abstract not available

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Title to be confirmed – Dr János Réthelyi, School of Mental Health Sciences, Semmelweis University, Budapest

March 30 @ 12:30 pm - 1:30 pm
Seminar Room, Herchel Smith Building, Forvie Site.,

Abstract not available

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April 2017

Accelerating Development in Biomedical Engineering – Speaker to be confirmed

April 6 @ 9:00 am - 5:00 pm
St Catharine’s College,

Accelerating Development in Biomedical Engineering: Collaborations between clinicians, engineers and industry This event concentrates on the ‘how and why’ of collaborating in biomedical engineering. It will show how researchers, clinicians and industry can work together to solve medical and healthcare challenges. The event will have sessions on medical devices, biomechanics, and imaging and informatics, together with discussions on overcoming barriers to collaboration. It also provides the opportunity to meet representatives of the Cambridge biomedical companies and to discuss technical problems…

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Title to be confirmed – Dr Simon Kyle,Nuffield Department of Clinical Neurosciences, Sir William Dunn School of Pathology, University of Oxford

April 6 @ 12:30 pm
Seminar Room, Herchel Smith Building, Forvie Site.,

Abstract not available

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Sleep and mental health – Dr Simon Kyle,Nuffield Department of Clinical Neurosciences, Sir William Dunn School of Pathology, University of Oxford

April 6 @ 12:30 pm - 1:30 pm
Seminar Room, Herchel Smith Building, Forvie Site.,

Abstract not available

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Functional neuromarkers for psychiatry – Dr Juri Kropotov Laboratory of Neurobiology of Action Programming at the Institute of the Human Brain

April 12 @ 12:30 pm - 1:30 pm
Lecture Theatre, MRC Cognition and Brain Sciences Unit, Chaucer Road,

The paper describes a recently emerged methodology of extracting functional neuromarkers from spontaneous multi-channel EEG, event-related de/synchronization, and event-related potentials (ERP). The methodology includes methods of blind source separation for artifact correcting and extracting latent (hidden) components from resting state EEG and from event-related potentials, methods for constructing normative and patient databases, for comparing the extracted individual parameters with the normative data, as well for pre-post comparison. The high test-retest reliability of neuromarkes, the high level of specificity and sensitivity…

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Longevity and anticancer mechanisms in the naked mole rat – Prof. Vera Gorbunova

April 12 @ 3:00 pm - 4:00 pm
Department of Pharmacology Lecture Theatre, Tennis Court Road,

Abstract not available

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Removing tumours from within and around the brain – Dr Thomas Santarius

April 27 @ 4:00 pm - 5:00 pm
Hodgkin Huxley Seminar Room, Physiology Building, Downing Site,

Abstract not available

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Title to be confirmed – Professor Claus Lamm

April 28 @ 4:30 pm - 6:00 pm
Ground Floor Lecture Theatre, Department of Psychology,

Abstract not available

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