Professor of Neuroimmunology. Has been doing MS research in Cambridge since 1994. He is also a consultant neurologist. With Alastair Compston, he was very involved in the development of alemtuzumab as a treatment of MS.
Will is currently a Neurology registrar, in the last few months of his training. He did a PhD with Alasdair in Cambridge, Declan Chard in London and Tomas Kalincik in Melbourne. So far his work has involved:
- setting up the CCMR One trial and analysing the MRI endpoints
- demonstrating by MRI that there is a periventricular MTR gradient in MS [Brown JWL Brain. 2017 PMID: 28043954 and Brown JWL, Mult Scler. 2020 PMID: 30957691] which can be modifed by immunotherapy [Brown JWL, Mult Scler. 2019 PMID: 31169059]
- using “Big Data” such as MSBase to compare the efficacy of disease modifying therapies in MS [Brown JWL JAMA 2019 PMID: 30644981 and He A, Merkel B, Brown JWL, Lancet Neurol. 2020 PMID: 32199096 and Kalincik T, Brown JWL, Lancet Neurol. 2017 PMID:
A neurology Trainee, doing a PhD, who joined the lab in 2018. He is interested in developing ways to measure remyelination in people with multiple sclerosis, especially using visual evoked potentials and measures of eye movements. He was involved in the CCMR-One Trial and is responsible for the CCMR Two trial. He has written a review on remyelination in MS [Cunniffe J Neurol 2019 PMID: 31190170 ].
Ed is a Neurology registrar with an interest in Neuroimmunology and Neurocritical Care. He is the Association of British Neurology Trainees representative for the East of England, and Secretary of the Neurocritical Care Scientific Group of the European Academy of Neurology. His research focusses on understanding the immunological processes behind severe Traumatic Brain Injury (TBI), particularly the development of subsequent central nervous system autoimmunity [Needham EJ, J Neuroimmunol. 2019 PMID:31005712.]. And he has a passing interest in the neurology of COVID [Needham EJ, Neurocrit Care. 2020 PMID: 32346843].
Has been working as the Senior Research Nurse in the group since 2008, after a long career as a senior neurology nurse. She runs our trials day-to-day and is the main point of contact with trial participants.
Research Physiotherapist, who does all of our trial outcome assessments, including EDSS.